Fox-Fordyce disease (FFD), also known as apocrine miliaria or chronic . López- Ávila A, Ortiz S. Enfermedad de Fox-Fordyce con presentación clínica atípica. Request PDF on ResearchGate | Enfermedad de Fox-Fordyce | —Fox-Fordyce disease is an infrequent inflammatory disorder characterized by the appearance . Request PDF on ResearchGate | On Nov 1, , I. Ballester and others published Enfermedad de Fox-Fordyce con presentación clínica atípica.

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However, less frequent locations on the thorax, areolas, abdomen, and legs have been described. SRJ is a prestige metric based on the idea that not all citations are the same. Fox-Fordyce disease is an infrequent inflammatory disorder characterized by the appearance of pruritic papules with follicular distribution, localized in areas where apocrine glands are present. Si continua navegando, consideramos que acepta su uso. Patient reported that other females in her family had presented this skin condition in the armpits, although less severe.

Received Aug 18; Accepted Nov 3. Subscribe to our Newsletter. Histopathology showed dilated follicular infundibula with hyperkeratosis, as well as xanthomatous histiocytes with perifollicular distribution and discrete inflammatory lymphocytic infiltrate. Get free access to newly published articles Create a personal account or sign in to: Experimental production of asymptomatic form.

You can change the settings or obtain more information by clicking here. In the year has been indexed in the Medlinedatabase, and has become a vehicle for expressing the most current Spanish medicine and modern.

We report two cases with clinical diagnosis and histopathological confirmation, presenting perifollicular xanthomatosis on histological examination, recently described as a distinctive, consistent, and specific feature of this disease.


Intrafollicular mucin deposits were also observed Figure 5.

Si continua navegando, consideramos que acepta su uso. Create a free personal account to make a comment, download free article PDFs, sign up for alerts and more. Successful treatment of refractory pruritic Fox-Fordyce disease with botulinum toxin type A.

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If you are a member of the AEDV: Clinically, FFD is characterized by the presence of multiple skin-colored follicular papules, slightly yellowish or brown, dome-shaped, with a smooth surface, which may be accompanied by mild to moderate pruritus or even be asymptomatic.

Patterns histopathologic of Fox-Fordyce disease. Create a free personal account to download free article PDFs, sign up for alerts, and more. All articles are subjected to a rigorous process of revision in pairs, and careful editing for literary and scientific style.

Apocrine glands, Fox-Fordyce disease, Miliaria. Continuing navigation will be considered as acceptance of this use. Print Send to a friend Export reference Mendeley Statistics. Clinicopathological Study of Fox-Fordyce disease.

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HONselect – Fox-Fordyce Disease

Support Center Support Center. Definitive diagnosis is made by histopathological examination in which nonspecific findings such as intrafollicular corneal plug, hyperkeratosis, spongiosis, retention vesicles, glandular dilation with mucin deposits, and perifollicular lymphohistiocytic inflammatory infiltrate can be observed.

Concurring with Shelley and Levy’s suggestion 1 that an endocrinological approach to the study of this disorder might be the most rewarding, we have attempted to clarify some of the above foedyce through a series of hormonal studies performed in the. Fox-Fordyce disease FFDalso known as apocrine miliaria or chronic pruritic papular eruption of the pubis and fogdyce, affects areas where apocrine glands are found predominantly, such as the pubic, axillary, and anogenital regions.


Therefore, pelvic ultrasound was ordered, showing polycystic ovaries. We present a case of histologically confirmed Fox-Fordyce disease with high clinical expressivity in a year-old female. Indian J Sex Transm Dis. Please review our privacy policy. Punctate papules with follicular distribution in the armpits and hemorrhagic crusts due to scratching.

We present two cases with both clinical and histopathological diagnosis of perifollicular xanthomatosis. National Center for Enfemredad InformationU. Yellowish-brown punctate papules with follicular distribution coalescing in plaques and affecting fordyec armpits.

Fox-Fordyce disease: report of two cases with perifollicular xanthomatosis on histological image

SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. Go to the members area of the website of the AEDV, https: Purchase access Subscribe to JN Learning for one year.

Treatment response tends to be limited or partial; the lesions and symptoms may recur or persist. B – Negative membrane epithelial antigen C – Negative carcinoembryonic antigen in histiocytes.

Its etiopathogenesis is not clearly known, and it involves the obstruction of the apocrine excretory duct as an early phenomenon in the process.