Can you replace a humbucker with a single coil?

Humbucker neck slot, I can place a single coil pickup or single coil in humbucker slot Note the bridge slot can take a single coil or humbucker Ironstone Guitar single slot toaster Stratocaster pickup in a humbucker slot I fitted a strat pickup in a humbucker slot If you want a

single coil in humbucker slot Enter the Single Coil-Sized Humbuckers: all the huge, warm, harmonically rich power of a full-sized humbucker in a drop-in replacement, single